5-FU (????????®) ???? ????? ?????????????????? ??????? ???????????????????????? 5-FU ? ?? ??????????????? ??? ???? ?????????? ?????????? ?????????? ???????? ???? ?? ??????????????????? ?????????????????????? ?? ???????????????? ?? ?????????? ?????? (????®) ????????????? ?????? (????®) ????? ? colorectal cancer ???????????? ????? ??? ????